Anklam lies right in the centre of the glacial valley of the river Peene, close to the Baltic Sea and the island of Usedom. The river Peene, the only river in Germany that has not been regulated, runs through the town. The city itself is looking back on 800 years of history. It has long been a Hansa city and a border town which connected Southern Sweden and Brandenburg. Then and now, the two towers of the churches Saint Mary and Saint Nikolai charcterise the townscape - though both had been considerably damaged in the Second World War. But up to today, the two churches tower above the wide fields and nature reserves that range north and south of the river Peene.

Anklam is the centre of a region shaped by agriculture. Above all, the Peene and its glacial valley attract numerous tourists every year. The Peene is known to be Germany's most intact river and famous for its far-reaching river-bed as well as its untouched landscape. A popular former citizen of Anklam, Otto Lilienthal, the first person to fly, had taken his first attempts here in the Peene valley. Nowadays, his life and work is recognised in the Otto Lilienthal museum.